Gennova Biopharmaceuticals Limited

HEART-Heart attack Emergency Assuaged by Remote diagnosis and local Treatment

Health care access

Enabling quality cardiac care to rural and semi-urban population, which were hitherto inaccessible, by increasing reach of primary care facilities through remote diagnosis and treatment.

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Lead Organization

Gennova Biopharmaceuticals Limited

Pune, State of Maharashtra, India

http://www.gennovabio.com

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Project Summary

Heart attack is a leading cause of death and disability globally, due to absence of a convenient and immediate access to quality cardiac care leading to unacceptable delay to commence treatment. In India, absence of cardiologists at primary health centers compounded with the lack of awareness in patients of early onset of symptoms, leads to delay in timely diagnosis and treatment leading to loss of life and livelihood of families. A timely intervention can help to reduce mortality. Through this project, we plan to establish primary cardiac care capability, currently non-existent at the district-level hospital and empower them for enabling analysis and diagnosis by trained cardiologists from a remote command center and start commencement of an appropriate first-line of cardiac care at the primary point of care. The project would help in reduction of mortality and morbidity across the board by providing convenient and immediate access to quality cardiac care.

Problem Statement

Cardiovascular disease contributed to 28.1% of total death in India in 2016 and that remain high largely due to historic apathy to address to make pervasive immersive access to quality health care. India is estimated to lose $237 billion from the loss of productivity and spending on health care related to cardiovascular diseases over the last 10-year period. To address and understand this problem we have consulted policy makers, clinicians, health care provider, technology providers, molecular biologist, supply chain logistics. Other contemporary work albeit on smaller scale and our own pilot study involving 207 patients has resulted in reduced mortality, reduction in PCI, bought care time for critical patients to reach advance care center. We together with a clinical, biopharmaceutical and a technology partner bring a solution that can make a difference to the quality of life of economically deprived, quality cardiac care deprived, chronically and critically impaired population often being the sole earning member with 5-6 dependents. Lack of capacity at the primary care hospitals for cardiac related diagnosis or treatment, limited distribution of super specialty cardiac center and long travelling time to reach in clinically relevant time are major reasons for the current predicament. We intend to solve this problem by creating a hyper-local primary cardiac care centers, enabling timely reperfusion/stabilization and transport to appropriate care center, pervasive ubiquitous access through capacity building, conflation of advances in biopharmaceuticals and technology to contemporize cardiac care and by effective inclusion of all stake holder: Govt, clinicians, public, patients and provider.

Solution Overview

The problem can be solved by organizing cardiac health camps and dissemination of information, setting up adequately and appropriately equipped primary cardiac care center(PCCC), processing of ECGs by a centralized command center established to provide specialist diagnosis remotely, formal training to PCCC staff to commence first line of treatment based on prescription from command center or stabilized and triaged for transport to a tertiary medical center. In first two years of the project we will get consensus and buy-in from clinicians for adoption of this concept, prioritized list of PCCC will be planted culminating in the establishment of 2 command centers with failover mechanism and 10 pilot PCCC in operation. In 3rd year the operation will be scaled up 5-times to include a total of 60 PCCC. In 4th-5th year nationwide supply chain and operation management capability will be established and further mechanisms will be in place to penetrate through to 100 PCCC/year and formulate a self-sustaining/public-private funded mechanism to perpetuate the PCCC beyond the funding. Beyond 5th year, this project will lead establishment of cross substantiate concept, implementation and financial model to additional geographies. This set up of cardiac specialists to contemporary practices and treatment will improve access to cardiac care to <40km to patients, reduce cost of treatment (patient and provider), morbidity and mortality while upskilling manpower purposed for PCCC. As an indirect benefit awareness to patients and families in terms of care and management of cardiac problems will be imparted and invaluable epidemiological data will be generated.

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